Small molecules & cofactors

Small molecules and cofactors that are standard tools in metabolism and redox research. NAD+ is the central redox cofactor of every cell, AICAR is the classic laboratory activator of AMPK, 5-Amino-1MQ inhibits the enzyme NNMT, SLU-PP-332 activates the estrogen-related receptors, glutathione is the main antioxidant thiol in cells, and melatonin is the pineal hormone behind circadian research. Read our NAD+ research overview for one of the most studied molecules in this group.