99.38% HPLC
Pictured: 50 mg5-Amino-1MQ
Small molecules & cofactors · powder
Strength
Buy more, save more applies per product
Lab report · current batch
All reports- Identity (LC-MS)Confirmed
- SterilityNo growth
- Endotoxin (LAL)0.12 EU/mL
- Heavy metals (ICP-MS)< 0.1 ppm
Research overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small, membrane-permeable molecule that inhibits nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in fat tissue and liver. NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, so it sits at the junction of methylation and NAD+ metabolism.
Inhibiting NNMT is studied as a way to raise intracellular NAD+ and change fat-cell metabolism, and mouse studies with 5-Amino-1MQ reported reduced fat mass and adipocyte size on a high-fat diet. It is supplied as a research reagent for NNMT and metabolism studies, and 5-Amino-1MQ capsules are available for oral designs.
Further reading: NAD+ research: the cofactor behind energy metabolism, sirtuins and ageing
Product details
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). It is used in research on NNMT and cellular metabolism.
| Form | Powder, sealed vial |
|---|
Storage & handling
Keep unopened vials sealed, dry and protected from light at −20 °C for long-term storage. Short-term storage at 2-8 °C is acceptable. Handle according to your laboratory's procedures.
Shipping
Every order ships free with tracked delivery. You'll see the delivery options and estimated times at checkout, and get a tracking number and a tracking page when your order ships. Availability depends on your shipping destination.
Questions
What enzyme does 5-Amino-1MQ inhibit?
Nicotinamide N-methyltransferase (NNMT), which methylates nicotinamide.
How is NNMT linked to NAD+?
NNMT consumes nicotinamide, a building block of the NAD+ salvage pathway, so inhibiting it is studied as a way to support NAD+ levels.
What's in the vial?
5-Amino-1MQ at the strength you choose. No diluent or accessories are included.
Can I check the lab report for my vial?
Yes. The batch number on your vial matches a report on this page or in our lab report library, with a link to verify it on the lab's website where available.
Is this product for human use?
No. It's sold for laboratory research use only and isn't for human or veterinary use.
Previous batches
- No earlier batches published for this strength.




