99.38% HPLCNAD+
from$119.99
AICAR
Small molecules & cofactors · powder
$41.99per vial
Strength
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Lab report · current batch
All reportsAICAR · 50 mgCurrent batch
The lab report for the batch we're shipping is being prepared. It will appear here as soon as it's published.
Research overview
AICAR (acadesine, 5-aminoimidazole-4-carboxamide ribonucleoside) is a cell-permeable nucleoside that cells convert into ZMP, a mimic of AMP. ZMP activates AMP-activated protein kinase (AMPK), the cell's central energy sensor, without changing the cell's actual energy charge.
Since the 1990s AICAR has been the standard laboratory tool for activating AMPK in cells and animals, used in research on glucose uptake, fatty-acid oxidation and mitochondrial biogenesis. ZMP also affects other AMP-sensitive enzymes, so AMPK-independent effects should be ruled out with suitable controls, such as AMPK-deficient cells. Supplied as a powder for biochemical research.
Further reading: MOTS-c and SS-31: two peptides at the centre of mitochondrial research
Product details
AICAR (acadesine) is a cell-permeable nucleoside analog that activates AMP-activated protein kinase (AMPK) after conversion to ZMP. It is a standard reagent in AMPK research.
| Form | Powder, sealed vial |
|---|
Storage & handling
Keep unopened vials sealed, dry and protected from light at −20 °C for long-term storage. Short-term storage at 2-8 °C is acceptable. Handle according to your laboratory's procedures.
Shipping
Every order ships free with tracked delivery. You'll see the delivery options and estimated times at checkout, and get a tracking number and a tracking page when your order ships. Availability depends on your shipping destination.
Questions
How does AICAR activate AMPK?
Cells convert it to ZMP, which mimics AMP and switches on AMPK.
Does AICAR act only on AMPK?
No. ZMP can affect other AMP-sensitive enzymes, so good studies include controls for AMPK-independent effects.
What's in the vial?
AICAR at the strength you choose. No diluent or accessories are included.
Can I check the lab report for my vial?
Yes. The batch number on your vial matches a report on this page or in our lab report library, with a link to verify it on the lab's website where available.
Is this product for human use?
No. It's sold for laboratory research use only and isn't for human or veterinary use.
Previous batches
- No earlier batches published for this strength.
50 mg$41.99
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