

IGF-1 LR3
Growth-factor & GH fragments · lyophilized powder
Strength
Buy more, save more applies per product
Lab report · current batch
All reports- Identity (LC-MS)Confirmed
- SterilityNo growth
- Endotoxin (LAL)0.03 EU/mL
- Heavy metals (ICP-MS)< 0.1 ppm
Research overview
IGF-1 LR3 is a recombinant analogue of insulin-like growth factor 1 with 83 amino acids: arginine replaces glutamate at position 3, and a 13-amino-acid extension is added at the N-terminus. These changes greatly reduce binding to IGF-binding proteins, so more of the peptide stays free and active.
As a result it is far more potent than native IGF-1 in many cell systems and lasts longer, which is why it is widely used as a cell-culture and bioprocessing reagent to support cell growth in serum-free media. It is a standard tool for IGF-1 receptor signalling studies through the PI3K-Akt and MAPK pathways. Supplied lyophilized; use low-binding tubes for dilute solutions.
Product details
IGF-1 LR3 is a recombinant analog of insulin-like growth factor 1 with an arginine substitution at position 3 and a 13-amino-acid N-terminal extension that reduces binding to IGF-binding proteins. It is widely used as a cell-culture reagent.
| Form | Lyophilized powder, sealed vial |
|---|
Storage & handling
Keep unopened vials sealed, dry and protected from light at −20 °C for long-term storage. Short-term storage at 2-8 °C is acceptable. Handle according to your laboratory's procedures.
Shipping
Every order ships free with tracked delivery. You'll see the delivery options and estimated times at checkout, and get a tracking number and a tracking page when your order ships. Availability depends on your shipping destination.
Questions
What does LR3 mean?
Long arginine 3: a 13-amino-acid N-terminal extension (long) plus arginine at position 3.
Why is IGF-1 LR3 used in cell culture?
It binds IGF-binding proteins poorly, so more stays active, making it a potent growth supplement for serum-free media.
What's in the vial?
IGF-1 LR3 at the strength you choose. No diluent or accessories are included.
Can I check the lab report for my vial?
Yes. The batch number on your vial matches a report on this page or in our lab report library, with a link to verify it on the lab's website where available.
Is this product for human use?
No. It's sold for laboratory research use only and isn't for human or veterinary use.
Previous batches
- IGF0766 · 2026-05-2999.28%




