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MOTS-c research peptide

MOTS-c

Mitochondrial & cellular-aging research · lyophilized powder

99.31% HPLC purityBatch-tested by ElementrixResearch use only
$79.99per vial

Strength

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Lab report · current batch

All reports
MOTS-c · 10 mgBatch MOT-260708-Y1 · Tested Jul 8, 2026
99.31%HPLC purity
  • Identity (LC-MS)See report
  • SterilityNo growth
  • Endotoxin (LAL)0.05 EU/mL
  • Heavy metals (ICP-MS)< 0.1 ppm
View report (PDF)
Research overview

MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame inside the mitochondrial 12S rRNA gene, one of the first peptides found to be encoded in mitochondrial DNA. It acts mainly on skeletal muscle, where it inhibits the folate pathway and purine synthesis, leading to activation of the energy sensor AMPK.

In mice, MOTS-c prevented insulin resistance caused by ageing and a high-fat diet and improved physical capacity in young, middle-aged and old animals, and exercise raises its levels in human muscle and blood. It contains methionine, so keep it sealed and dark. Read MOTS-c and SS-31.

Further reading: MOTS-c and SS-31: two peptides at the centre of mitochondrial research · NAD+ research: the cofactor behind energy metabolism, sirtuins and ageing

Product details

MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome (12S rRNA region). It is used in research on mitochondrial-derived peptides and cellular metabolism.

FormLyophilized powder, sealed vial
Storage & handling

Keep unopened vials sealed, dry and protected from light at −20 °C for long-term storage. Short-term storage at 2-8 °C is acceptable. Handle according to your laboratory's procedures.

Shipping

Every order ships free with tracked delivery. You'll see the delivery options and estimated times at checkout, and get a tracking number and a tracking page when your order ships. Availability depends on your shipping destination.

Questions

Where is MOTS-c encoded?

In mitochondrial DNA, within the 12S ribosomal RNA gene.

How does MOTS-c act on metabolism?

It inhibits the folate pathway and purine synthesis in muscle cells, which activates AMPK.

What's in the vial?

MOTS-c at the strength you choose. No diluent or accessories are included.

Can I check the lab report for my vial?

Yes. The batch number on your vial matches a report on this page or in our lab report library, with a link to verify it on the lab's website where available.

Is this product for human use?

No. It's sold for laboratory research use only and isn't for human or veterinary use.

Previous batches
10 mg$79.99
1

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For laboratory research use only. Not for human or veterinary use. You must be 21 or older to order.